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Essential information on anti drugs of ischemic heart disease

Anti-ischemic drug Trimetazidine retains the metabolism of cells that have been exposed to the ischemia and hypoxia energy. Angina patients treated with this drug shown increases coronary flow reserve.

Doctors prescribe Trimetazidine for the treatment of angina pectoris. This metabolic drug anti-ischemic or anti-anginal helps improve the utilization of glucose myocardial by inhibition of metabolism of fatty acids.

Mechanism of action:

Mentioned by name brand, MR Vastarel Trimetazidine is available in Tablet 35 mg dose form. Metabolism of cells are exposed to the ischemia and hypoxia energy may be retained with the help of this drug that prevents that the reduction in intracellular adenosine triphosphate levels. The present drug ensures the flow of sodium potassium enhanced transmembranous and proper functioning of ionic pumps as well as maintaining cellular homeostasis. Also, is known to inhibit oxidation of fatty acids in the blood vessels.

Important information

Trimetazidine is taken with a full stomach. Not recommended for use by pregnant women, lactating women, or people with hypersensitivity. Adverse reactions to this drug include vomiting, nausea, and gastrointestinal disorders. In some countries, Trimetazidine is marketed as a treatment for tinnitus and dizziness. This is due to the fact that you have a high profile safety and tolerability, with no known drug interactions.

Other therapeutic benefits

Trimetazidine is also known for its cardioprotective effects as confirmed in human isquemia-reperfusion. The drug works in patients who undergo bypass with the arrest of cardioplegica and percutaneous coronary revascularization surgery. Studies showed that a (MR) form of the modified version of this medication when taken twice a day, is bioequivalent to the previous formulation taken three times daily.

Meanwhile, controlled studies in patients with angina showed Trimetazidine increases coronary flow reserve and thus control quick sudden changes in blood pressure, significantly decreasing the frequency of angina attacks leader in the use of nitrate reduction.

For diabetic patients with coronary artery disease, Trimetazidine helps improve left ventricular function. Trimetazidine has demonstrated efficacy in the treatment of patients with heart failure. It is recommended to consult your doctor before taking this medicine.