Wednesday, November 17, 2010

History of Wonder drug?

How did as controversial as it has today become an opioid antagonist naltrexone called? What is the story behind the emergence of low-dose naltrexone as a drug that has proved to be so beneficial to many diseases other than its operationalization.? These are some of the queries we discussed in this article.

Naltrexone is available in the form of Naltrexone Hydrochoride and is an antagonist of opioid and alcohol. This medication used in the dose of 50 mg/day, blocks the action of the part of the brain that feels pleasure (meaning the receptors for alcohol and opiates) on the use of alcohol or opiates.However, many researchers found other uses for naltrexone, at much lower doses, for other diseases demasiado.Esta is the use of Naltrexone, called low-dose naltrexone, which has proved to be a controversial topic bitterly with supporters and detractors.

Firstly, Naltrexone was patented by a small laboratory called laboratories Endo, way back in 1967, after discovering this drug in 1963. Endo laboratories was one of the pioneers in the field of research on alcohol and drugs at the time. Later, the pharmaceutical giant DuPont acquired Endo laboratories.It is doubtful if DuPont would continue to fund research and the use of the drug 1970s, naltrexona.Alrededor United States Government began to investigate and actively support the use of naltrexone as a remedy for various addictions, including alcohol and opiates (including heroin addiction). DuPont would receive financial and clinical support in testing the drug naltrexone.

Growing pains: while the new drug testing addiction naltrexone, it was found that many drug addicts prefer methadone to overcome addiction, instead of naltrexone. Another point that caused concern was the elevation of liver enzymes while using naltrexone.

Much later, several medical teams began experimenting with the use of Naltrexone for uses other than the addiction. This triggered the first controversy about this drug.Some researchers found that naltrexone in much smaller (from low-dose naltrexone) dose could be used to control other diseases as varied as certain forms of cancer, AIDS, Crohn's disease, multiple sclerosis and fibromyalgia.However, while the naltrexone had the approval of the FDA for the treatment of addiction, is difficult, without expensive, clinical research to get approval by the FDA for the use of low-dose naltrexone.Despite this, many patients have gone in front with the use of low dose naltrexone for various diseases mentioned above and have reported their success on the internet and in other fora.This is the reason for the controversy over the use of low-dose naltrexona.Mayor part of conventional medical personnel will never promote its use for disease Crohn, MS (multiple sclerosis) or other diseases that are still little entendidos.Sin however, these diseases patients have not able to obtain relief for symptoms of drugs approved by FDA often towards recognized modern medicine residency area beyond drugs and therapies alternativas.Baja tried dose of Naltrexone is one of those drugs; without adequate research, low-dose Naltrexone can never reach the doctor prescription pad and will remain extremely controversial.

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